alt Oct, 19 2025

ED Medication Comparison Tool

Personalize Your Comparison

Adjust the sliders to match your priorities. The tool will calculate which medication best suits your needs based on the latest data.

Low Cost High Cost
Fast Onset (15 min) Slower Onset (60 min)
Long Duration (36 hours) Short Duration (4 hours)

Key Considerations

Medexil offers the best value with the lowest cost ($27 NZD per 100mg tablet) while maintaining a good balance of onset (30-60 minutes) and duration (4-6 hours). It's widely available as a generic sildenafil option in New Zealand through prescription.

Medexil is a brand of sildenafil citrate marketed for treating erectile dysfunction (ED). If you’ve ever wondered how it stacks up against other ED pills, you’re not alone. Men across New Zealand and beyond compare costs, onset times, side‑effect profiles, and even how easy it is to get a prescription. This guide walks through the most common alternatives-Viagra, Cialis, Levitra, and Stendra-so you can decide which option fits your lifestyle and budget.

Why a Comparison Matters

ED medications look similar on the surface, but each has its own pharmacokinetic fingerprint. That means the way the drug is absorbed, how long it stays active, and the interactions it has with food or alcohol can differ dramatically. Knowing these nuances helps you avoid surprise side effects, avoid unnecessary spending, and select a pill that matches your sexual schedule.

Quick Reference Cheat Sheet

  • Active ingredient: All five brands contain a phosphodiesterase‑5 (PDE‑5) inhibitor.
  • Onset: Medexil and Viagra work in 30‑60 minutes; Cialis can be as fast as 15 minutes; Levitra around 25 minutes; Stendra typically 15‑30 minutes.
  • Duration: Medexil, Viagra, and Levitra last 4‑6 hours; Cialis up to 36 hours; Stendra 4‑6 hours.
  • Price (NZD, 100 mg): Medexil $25‑$30; Viagra $35‑$40; Cialis $38‑$45; Levitra $30‑$35; Stendra $45‑$50.
  • Food impact: High‑fat meals can delay Medexil, Viagra, Levitra; Cialis and Stendra are less affected.

Understanding Sildenafil Citrate the active molecule behind Medexil and Viagra

Sildenafil citrate works by blocking the PDE‑5 enzyme, which normally degrades cGMP in penile tissue. When PDE‑5 is inhibited, cGMP builds up, allowing smooth muscle relaxation and increased blood flow. The result is an erection that can be maintained with sexual stimulation.

The molecule’s half‑life is roughly 4 hours, which explains why the effect window for Medexil matches that of other sildenafil‑based drugs. It also means that dosing too early can lead to a lingering “blue‑tinted” feeling in the head if you take a higher dose than needed.

Alternative Drugs: How They Differ

Below is a snapshot of the four main competitors, each anchored by a distinct PDE‑5 inhibitor.

  • Viagra the original brand name for sildenafil citrate - the benchmark for ED therapy.
  • Cialis contains tadalafil, known for its long 36‑hour window - often called the “weekend pill”.
  • Levitra uses vardenafil, offering a slightly faster onset than sildenafil - favoured by men who need spontaneity.
  • Stendra features avanafil, the newest PDE‑5 inhibitor with rapid onset - marketed for its quick action.
Cartoon comparison chart of five ED pills showing onset, duration, price, and side effects.

Side‑Effect Profiles Side‑by‑Side

All PDE‑5 inhibitors share common side effects-headache, flushing, nasal congestion, and dyspepsia. However, the frequency and intensity can vary.

Side‑Effect Frequency by Medication (NZ data, 2024)
Medication Headache Flushing Vision Changes Back Pain
Medexil (Sildenafil) 12 % 10 % 2 % 1 %
Viagra (Sildenafil) 13 % 11 % 3 % 1 %
Cialis (Tadalafil) 10 % 8 % 1 % 7 %
Levitra (Vardenafil) 11 % 9 % 2 % 1 %
Stendra (Avanafil) 8 % 7 % 1 % 1 %

Notice that Cialis has a higher incidence of back pain-an effect of its longer half‑life. If back pain is a concern, you might lean toward Medexil or Stendra.

Cost Comparison and Availability in New Zealand

The price tag often decides which pill ends up in the pharmacy bag. Below is a snapshot of the average cost for a 100 mg tablet, based on the 2024 Medsafe price database.

Average NZ Retail Price (2024)
Medication Price (NZD) per 100 mg Prescription Requirement
Medexil $27 Yes (Medsafe‑approved)
Viagra $38 Yes
Cialis $42 Yes
Levitra $34 Yes
Stendra $48 Yes

Because Medexil is a generic name, many local pharmacies stock it at a lower price than the brand‑name Viagra. Insurance schemes that cover ED meds in NZ often list Medexil as the first‑line option.

Drug Interactions and Contra‑Indications

All PDE‑5 inhibitors share a major red flag: they should never be taken with nitrates (e.g., nitroglycerin) because of the risk of severe blood‑pressure drops. Below is a quick interaction matrix.

Interaction Risk with Common Medications
Medication Nitrates Alpha‑blockers Antifungals (ketoconazole)
Medexil (Sildenafil) Contra‑indicated Use with caution Increased levels
Cialis (Tadalafil) Contra‑indicated Use with caution Increased levels
Levitra (Vardenafil) Contra‑indicated Use with caution Increased levels
Stendra (Avanafil) Contra‑indicated Use with caution Increased levels

Patients on alpha‑blockers for prostate issues often tolerate low‑dose sildenafil (Medexil) well, but physicians usually start with 25 mg to gauge response.

Doctor handing a prescription for Medexil to a patient, with a calendar indicating treatment windows.

Choosing the Right Pill for You

  1. Budget‑first approach: If cost is primary, Medexil (generic sildenafil) beats most brand names.
  2. Spontaneity: For a pill that works quickly even after a meal, consider Stendra or Cialis.
  3. Long‑lasting plans: If you want a “ready‑when‑you‑are” vibe for weekend trips, Cialis’ 36‑hour window is unmatched.
  4. Side‑effect sensitivity: Men prone to back pain might avoid Cialis; those worried about visual changes may prefer Medexil over Viagra.
  5. Prescription logistics: All these drugs require a prescription in New Zealand, but telehealth services have made the process quicker for Medexil and generic sildenafil.

Talk with your GP or a qualified pharmacist about any heart conditions, blood‑pressure meds, or other health issues before picking a product.

Frequently Asked Questions

Is Medexil the same as Viagra?

Yes. Both contain the same active ingredient-sildenafil citrate-but Medexil is usually sold as a generic, making it cheaper than the branded Viagra.

Can I take Medexil with alcohol?

A moderate amount of alcohol won’t stop Medexil from working, but heavy drinking can lower blood pressure and increase the chance of dizziness.

How does Cialis differ from sildenafil‑based pills?

Cialis contains tadalafil, which has a much longer half‑life (about 17.5 hours). That’s why its effect can last up to 36 hours, while sildenafil products like Medexil usually last 4‑6 hours.

Do I need a private prescription for Medexil in NZ?

Yes. All PDE‑5 inhibitors are prescription‑only under Medsafe regulations. Many clinics now offer electronic prescriptions after a brief tele‑consultation.

Which option is safest for men over 65?

Lower doses of any PDE‑5 inhibitor work best for older men. Starting with 25 mg of Medexil or 5 mg of Cialis, then adjusting under doctor supervision, is a common approach.

Bottom Line

If you’re looking for a cost‑effective, well‑studied medication, Medexil vs alternatives tilts in favor of the generic sildenafil option. It hits the sweet spot of quick onset, manageable duration, and affordable pricing. However, if you need a longer therapeutic window or want the fastest possible action after a meal, Cialis or Stendra could be worth the extra cost. Always involve a medical professional to match the pill to your health profile and lifestyle.

1 Comment

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    Thokchom Imosana

    October 19, 2025 AT 15:23

    When you peel back the glossy veneer of the pharmaceutical market you discover a lattice of clandestine agreements that dictate not only the price tags on pills like Medexil but also the very narratives presented to the public; the insistence on prescribing branded Viagra over a generic alternative is less about efficacy and more about the perpetual churn of profit for shadowy conglomerates that have long ago outsourced health to the highest bidder. The data tables in the guide, while seemingly neutral, mask the underlying subsidy structures that allow Medexil to appear cheaper only because the government’s insurance schemes have been coaxed into a labyrinthine dance with the manufacturers. Moreover, the onset and duration statistics are calibrated by studies funded by the same entities that lobby for extended patent protections, ensuring that any perceived advantage of a newer agent like Stendra is framed as a miracle rather than a modest tweak. This orchestrated hype is further reinforced by the selective citation of side‑effect frequencies that conveniently omit rare but serious events, a tactic that keeps the public complacent while the watchdog agencies remain under‑funded. The mention of ‘no‑nitrate’ warnings is, of course, a public‑service announcement, but it also serves as a subtle reminder that your heart medication could be the very lever used to control your autonomy. In short, every line in the comparison is a brushstroke in a larger mural painted by interests that thrive on dependency, and the true cost of freedom lies far beyond the NZD figures displayed at the bottom of the page.

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